PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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FOREWORD+ V7 }* }% |( N6 L
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.  Y( k" g/ l- u3 M  n
Making this potential a reality requires an international effort. The recognition
% z* b& e8 u2 Nthat such a promising yet multifaceted discipline needs fostering led to the establishment
* N# I: s) H. v+ x. s3 t. @of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the/ ^7 k7 b+ `6 Y/ A
ISSCR is the development of tools to ensure the success of stem cell researchers. What
* p. B: ]) W8 w2 Q3 Obetter way to do this than to collaborate with Current Protocols to develop this valuable( h) o- p- B6 U: [& M+ l0 L8 F4 U
compendium of protocols in stem cell biology?
+ W+ J% R, C4 Y" ?Stem cell researchers have developed a number of breakthrough techniques, from the: w  x- W( ~0 k5 j
derivation and manipulation of pluripotent embryonic stem cells to purification and
" w: W1 z+ }& ^transplantation of tissue-restricted stem cells from adult organs. A number of laboratories
$ d# f+ i) E2 S, O, q# R' hhave become leaders in the field as a result of developing such techniques. The more8 @* W% X+ b* x4 g" C
efficient scientists are at implementing new and powerful methodologies in their own5 y0 S4 Q6 \4 U
laboratories, the faster stem cell biology will advance our understanding of normal9 ?7 ?* v: h2 B5 H; t) r
development and lead to the development of therapies. Thus, the availability of quality$ E+ g% ^' d/ r
protocols will have amajor impact on the success of the entire field. Current Protocols has
+ L+ ^" [5 W0 {  F1 x* }* glong been the premier volume for proven in-depth protocols regarding many aspects of
0 g$ N* v- }3 ~& A6 k3 Tbiology, and this volume on stem cell biology will prove a valuable addition to researchers$ v* }0 ^5 x8 a/ B5 {
worldwide.
4 o( W4 Q) A0 xExperiments in stem cell biology must be interpreted with great caution as well as
/ I  o6 j, Q) w6 m0 e7 t1 [8 Jopenness to alternative explanations. For example, the recently discovered phenomenon& r& z( V4 O$ L# y5 f, y6 P: {; w
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral, ~% k8 ]4 s3 ?( H: \
tissues were initially misinterpreted as evidence for stem cell trans-differentiation.
- R0 u3 S; u$ ~# @  E) ^( AIt is very important that this compendium of protocols highlight potential pitfalls as well
( \5 s+ M8 C* Y" H* X  aas maintain the opportunity for clarification and correction when the need arises. The$ M' c8 h% r. h& G9 o
fact that these protocols will be provided online will help ensure that researchers always- L; H6 U/ R* B- ^  R
have the latest, most up-to-date protocols available to them., _$ Y3 }4 L* w3 G
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine
" h1 |- E: W4 J2 q' npush to share information and interact so that the field can move forward quickly. There& W& W! v7 k* b$ R5 l7 n6 [
is a drive to develop not only excellent basic research skills but to bring the findings% ?3 ]4 h# j& s3 X* B' ?
to clinical use so that patients can benefit. As a Hematology Attending Physician at& [3 n5 I8 S! r1 U2 c
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
" V8 J! t2 k( J' qand am drawn by the need to translate our research findings into therapies to help treat a
, \( Q" \7 |3 ~" I3 w' j, E! E8 B9 lnumber of diseases. The promise is great, but we need to deliver, and I believe Current! V9 g, Q% v; v: j- X! v2 R
Protocols in Stem Cell Biology will help tremendously.
: N; f" l4 Y6 N- x$ m  VLeonard I. Zon* P+ [' R4 H) a' E; T+ P6 j
Current Protocols in Stem Cell Biology
7 y  \2 ~  P+ N, t. {  HPublished online June 2007 in Wiley Interscience (www.interscience.wiley.com).
9 H6 H( d2 Y* w0 E# T: H) IDOI: 10.1002/9780470151808.scfores1% r0 y( s4 @" t* c
Copyright C
2007 John$ T) I4 N- g5 G0 F

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xiaodongqin

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Jonathan

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zpzp0312

谢谢楼主！

zisu_yu

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王乾

感谢你的大力支持！

horst

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dragon513

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