PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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FOREWORD. Q5 x( Z3 D# ^1 L
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.& k- _3 \4 P$ r8 P
Making this potential a reality requires an international effort. The recognition
; Q2 h; K( C+ \" R5 C, k0 Q6 W: nthat such a promising yet multifaceted discipline needs fostering led to the establishment
  r& o  D% t7 }3 aof the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
- G6 k" ]1 v& L/ ^* YISSCR is the development of tools to ensure the success of stem cell researchers. What
  Y9 T5 Z4 A9 b" C2 |) }better way to do this than to collaborate with Current Protocols to develop this valuable
  _  y. h/ N! V1 X! `compendium of protocols in stem cell biology?
  x, X) J* `+ F2 s! H! s/ Z5 nStem cell researchers have developed a number of breakthrough techniques, from the" F% N4 |! Z( Y& W5 l
derivation and manipulation of pluripotent embryonic stem cells to purification and) e4 _8 z8 U' Z
transplantation of tissue-restricted stem cells from adult organs. A number of laboratories
+ l. u- U: z! X1 ~have become leaders in the field as a result of developing such techniques. The more
- S/ [& v' M9 S3 N3 d0 c: tefficient scientists are at implementing new and powerful methodologies in their own1 j) U2 _& H" L& m
laboratories, the faster stem cell biology will advance our understanding of normal2 J0 w! [- G' [# }
development and lead to the development of therapies. Thus, the availability of quality. \% F1 V: Y- P& ^( P, K# i
protocols will have amajor impact on the success of the entire field. Current Protocols has( y% `+ Y6 L: h% N& D4 b5 }
long been the premier volume for proven in-depth protocols regarding many aspects of- }' p  `! \+ I9 P/ `9 P1 n3 F
biology, and this volume on stem cell biology will prove a valuable addition to researchers
1 m% t1 P, C: b9 W  Jworldwide.0 s% a" F% g" \3 g
Experiments in stem cell biology must be interpreted with great caution as well as4 k+ |7 r# l$ E8 Y* d
openness to alternative explanations. For example, the recently discovered phenomenon2 R% h8 p; j2 ~3 E* r' j- Q( x1 i4 r
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral5 i3 ?) \/ o/ a4 I5 f7 J* H
tissues were initially misinterpreted as evidence for stem cell trans-differentiation.
) F$ q+ |/ h3 H( T. X8 Z) @  w1 sIt is very important that this compendium of protocols highlight potential pitfalls as well
$ y) t; p$ z% z1 M& A! ]" Y/ V+ c& Qas maintain the opportunity for clarification and correction when the need arises. The
- t* z& i; _4 Zfact that these protocols will be provided online will help ensure that researchers always
5 t0 X( c, X# C( |6 |2 p0 Ehave the latest, most up-to-date protocols available to them.
8 a4 x* o+ y# y  R- u3 o5 L! ]# _The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine
2 ~! u6 q9 Z3 ~' V: w+ mpush to share information and interact so that the field can move forward quickly. There
9 O+ d  X% U# fis a drive to develop not only excellent basic research skills but to bring the findings
" g4 j! L: e- r& [( o6 n5 e, ^& k3 cto clinical use so that patients can benefit. As a Hematology Attending Physician at/ s6 x0 s$ ^7 w7 Z% T3 N7 q
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
4 U- c% K8 J% Y, Kand am drawn by the need to translate our research findings into therapies to help treat a7 V5 p5 X4 n, b7 d; L+ H
number of diseases. The promise is great, but we need to deliver, and I believe Current
$ t, K% O! R! Q! @* C4 N, h3 J; sProtocols in Stem Cell Biology will help tremendously.
$ s  U$ n' S. P$ ^# n/ }5 nLeonard I. Zon
' a5 V: C% O2 l5 R! p6 kCurrent Protocols in Stem Cell Biology6 c! ]+ Z' S. M" x
Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).4 e5 L) e0 O) o# i
DOI: 10.1002/9780470151808.scfores1/ c6 h  m& l6 t. o) x. F
Copyright C
2007 John5 B# h# p; W% e+ K
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xiaodongqin

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Jonathan

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zpzp0312

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zisu_yu

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王乾

感谢你的大力支持！

horst

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dragon513

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