PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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FOREWORD
  J0 O8 B. j& e) LStem cell biology is emerging as a field in biology with tremendous therapeutic potential.
. c0 C8 A% R: qMaking this potential a reality requires an international effort. The recognition
& e- E/ Z1 Q' `$ G8 Y  A) X  K3 bthat such a promising yet multifaceted discipline needs fostering led to the establishment# F6 D) w3 Q2 N. i
of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
, t1 b6 c2 Q2 V! O  A5 X2 wISSCR is the development of tools to ensure the success of stem cell researchers. What
4 |: ?5 g- B: Y7 w" d2 F8 Xbetter way to do this than to collaborate with Current Protocols to develop this valuable- {* L: P4 ?% H
compendium of protocols in stem cell biology?8 H* A& S$ O! a( X& ~
Stem cell researchers have developed a number of breakthrough techniques, from the
4 U# P4 ]# w9 u1 ^derivation and manipulation of pluripotent embryonic stem cells to purification and
$ ]  A! I' }5 P* R6 \6 V8 W( t( otransplantation of tissue-restricted stem cells from adult organs. A number of laboratories
9 c; r$ u% s3 Q! `" g( n( hhave become leaders in the field as a result of developing such techniques. The more2 V% {& }% h3 A( V; `' Q# ?
efficient scientists are at implementing new and powerful methodologies in their own
  ?  {! ?& M, H1 h' r' q0 M, Wlaboratories, the faster stem cell biology will advance our understanding of normal. h9 ~" y- f( o. F# m
development and lead to the development of therapies. Thus, the availability of quality
2 v4 |  ?5 V$ D2 W* wprotocols will have amajor impact on the success of the entire field. Current Protocols has
, N& g0 A4 [6 W. V4 }; s' hlong been the premier volume for proven in-depth protocols regarding many aspects of
; [. Y# Y( e* y. e* [biology, and this volume on stem cell biology will prove a valuable addition to researchers
- {1 P8 i/ K( @worldwide.
- V+ r* o$ N3 Z8 z4 a/ y$ yExperiments in stem cell biology must be interpreted with great caution as well as  b" i. b% i- y3 \, F
openness to alternative explanations. For example, the recently discovered phenomenon1 m7 N  y7 S9 Q* {( S) B
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral& G2 [: L6 n( t4 V0 B+ z
tissues were initially misinterpreted as evidence for stem cell trans-differentiation.  G  i+ v1 d: H! u  a: i  u
It is very important that this compendium of protocols highlight potential pitfalls as well1 D3 l7 T& C& j( @0 G& H9 |7 h
as maintain the opportunity for clarification and correction when the need arises. The$ M- d: s6 y/ j+ @( p
fact that these protocols will be provided online will help ensure that researchers always
, ]% S9 Y& s' Z1 xhave the latest, most up-to-date protocols available to them.
6 p6 {1 w$ c, [+ r7 K$ b) xThe stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine( m' G( W! s4 J" l# d7 N
push to share information and interact so that the field can move forward quickly. There
& I8 D/ W; x4 c. J7 U. zis a drive to develop not only excellent basic research skills but to bring the findings
$ @. `3 |/ y3 Y) ?* R$ y9 `to clinical use so that patients can benefit. As a Hematology Attending Physician at
9 Z5 Q  l+ D: M9 M+ AChildren’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
% J4 T# B2 J' Q$ Nand am drawn by the need to translate our research findings into therapies to help treat a
% n( x: t( P4 G+ a8 b# m% F, Fnumber of diseases. The promise is great, but we need to deliver, and I believe Current
  X7 c4 l5 Z) l( S5 IProtocols in Stem Cell Biology will help tremendously.
2 K; Z- }9 W' }1 E0 d/ j  Z( l6 b% o0 |Leonard I. Zon
. P( `9 W! U) Y7 KCurrent Protocols in Stem Cell Biology
1 Q/ A9 A, C' u: c$ x7 \Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).8 G9 s8 z1 O+ i2 X
DOI: 10.1002/9780470151808.scfores1
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2007 John
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7 s! `3 L0 s! g0 s6 m! Q$ Z附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了+ M  m5 [% F. x) d

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xiaodongqin

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Jonathan

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horst

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dragon513

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