PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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0 [3 N2 N8 i$ I& wFOREWORD' I. N" l$ X: I; V+ b% c( h/ j. L- X/ W
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.5 X& X0 L5 y0 U) M
Making this potential a reality requires an international effort. The recognition
0 ~! \. I. S- m- q3 Q1 athat such a promising yet multifaceted discipline needs fostering led to the establishment  m& x1 G% N' z  F% h8 e
of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
4 z0 I5 x% g- N* ?; K1 T! _ISSCR is the development of tools to ensure the success of stem cell researchers. What: I, V2 b$ j6 e
better way to do this than to collaborate with Current Protocols to develop this valuable
/ }: `8 r# R% ccompendium of protocols in stem cell biology?
/ _! |' n4 F/ Z' B5 t" J9 H5 LStem cell researchers have developed a number of breakthrough techniques, from the7 O5 j& |, E1 T+ W, O
derivation and manipulation of pluripotent embryonic stem cells to purification and) V) c: S- Q7 o0 H4 W* R5 ~& t* E
transplantation of tissue-restricted stem cells from adult organs. A number of laboratories
# v, F- r6 f3 X  u. Z8 s/ Mhave become leaders in the field as a result of developing such techniques. The more
- l: y* f# `6 x& refficient scientists are at implementing new and powerful methodologies in their own
( g) o/ c/ h4 d: l' Alaboratories, the faster stem cell biology will advance our understanding of normal
1 C1 G1 u* h+ A$ Cdevelopment and lead to the development of therapies. Thus, the availability of quality: _& \" C, r: W0 K: Q
protocols will have amajor impact on the success of the entire field. Current Protocols has/ g; q( h- ?6 E9 P
long been the premier volume for proven in-depth protocols regarding many aspects of2 b" i; z* |/ ~" Y2 Z3 T/ ~
biology, and this volume on stem cell biology will prove a valuable addition to researchers2 r7 M# t; H+ S( {
worldwide.
; V1 p: K5 K. q9 N2 YExperiments in stem cell biology must be interpreted with great caution as well as
1 @; U! n+ Z7 z& Uopenness to alternative explanations. For example, the recently discovered phenomenon8 `2 R/ j  Q" [; i
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral
% W* t8 |5 Z6 ]! q' Rtissues were initially misinterpreted as evidence for stem cell trans-differentiation.# D) A- [; q2 u) t: I" |! G: H, C# L
It is very important that this compendium of protocols highlight potential pitfalls as well
( c* T( z1 Y9 @2 V/ das maintain the opportunity for clarification and correction when the need arises. The& X( x9 T- G8 u0 l4 t0 S# U
fact that these protocols will be provided online will help ensure that researchers always& i* m1 c0 [, G. V% l8 e
have the latest, most up-to-date protocols available to them.! B1 @! G6 w' M. o3 p
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine. e* f7 {  P9 f" O8 t
push to share information and interact so that the field can move forward quickly. There
- \$ e1 Y- E% qis a drive to develop not only excellent basic research skills but to bring the findings
7 @5 h3 A* a" j/ Q& t; Xto clinical use so that patients can benefit. As a Hematology Attending Physician at5 d1 z" u, b1 b) F7 v
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia; p! K- F7 }$ a3 s
and am drawn by the need to translate our research findings into therapies to help treat a% g( G2 o$ Q  }* ]' f2 r! A  \
number of diseases. The promise is great, but we need to deliver, and I believe Current
3 Q% R8 A, [) M$ oProtocols in Stem Cell Biology will help tremendously.
9 _! L5 ]2 G3 w* ~/ w1 `2 }Leonard I. Zon( l6 a6 \$ h2 e$ `
Current Protocols in Stem Cell Biology
# t% D/ u7 F2 Y- o: n6 s4 c2 |Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).- Q: |' o: r5 r& k6 S
DOI: 10.1002/9780470151808.scfores1: _! ?* @  X1 l% n8 ?
Copyright C
2007 John
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8 u4 q8 I9 d0 D, U4 h/ Z  c3 e/ |附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了( G; u0 C1 {2 o# d6 q% H4 v( F

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xiaodongqin

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Jonathan

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