2008年Cell杂志的一期不错的干细胞特刊

yusheen

8 K) W( I9 P7 |0 x, W% U2 \4 y7 O+ X7 q! X% L) e
最近浏览期刊，发现2008年Cell杂志有一期干细胞研究的综述，内容非常全面，感觉对大家非常有用，可以作为教材来研究学习。下载时把文章的补充材料也下下来，供大家学习。
8 w% s$ I0 Z0 UStem cells have two remarkable abilities: they can self-renew to keep the stem cell pool replenished, and
( @& T2 p4 z; |% }they can differentiate into a wide variety of cell types. This stunning biological duality intrigues not only4 H% x9 v2 m( w# B/ p
those interested in the basic mechanisms of development, differentiation, and reprogramming, but- a- I* r  G2 I1 g
also those who seek to use stem cells therapeutically to replace lost or damaged tissue. But when did% {4 d+ @4 p2 R4 ^) k1 P
the stem cell revolution start? It was back in the 1960s that two Canadian researchers, Ernest A. McCulloch
( L. k, n& R) o: ?& F/ Wand James E. Till, launched the field of stem cell research with their groundbreaking work on the hematopoietic
3 \  E  p% L4 L( {4 ^stem cells of mouse bone marrow. By designing clonogenic assays to measure stem cell differentiation
4 d- L* g8 K6 C9 B0 Y3 Uin vitro and serial transplantation assays to study stem cell repopulating ability in vivo, Till and& k. l2 t6 j0 U$ D- O3 S3 z
McCulloch defined the hallmark characteristics of stem cells.( o3 n* b. z3 i2 a
The field of stem cell research has come a long way in 50 years, as we hope will be apparent from this
4 t, M7 S3 T6 A& I7 I5 ~year’s Special Review Issue. Our goal in this issue is to highlight the remarkable biological features of
5 U" @8 O# Q; W' hstem cells, the molecular pathways that control these characteristics, and the ways in which these enigmatic8 S3 R0 Z8 n8 m6 }1 d8 y+ z
cells can be exploited for cell replacement therapy. We would like to thank the many distinguished
& @* n2 u8 G' R7 ^experts who contributed their time and efforts as authors and reviewers to make this special issue on
7 u4 L- m* D2 L* F: q6 F' H/ ostem cells informative, thought-provoking, and timely. We hope that this collection of articles conveys
& R7 p9 y! B( `; kthe excitement and promise of stem cell research, as we enter a new era of possibility.

yusheen

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顶一个

chuanbaozang

赞一个

exin11

看看

flydayzhu

look 一下

linlicau

辛苦了，要点包包也能理解。

ayeqiu

下载看看~

ayeqiu

为啥每次都提示“你所在的用户组无法下载或查看附件”…………晕！晕！！晕！！！……

tpwang

回复 ayeqiu 的帖子/ b6 j% T& a! x$ A$ z7 A( K
. Z% p8 h+ @4 G- l# A; Q6 ?
你的积分还差9分就可以成为注册会员了，加油。5 _* y! }7 H) a: e

3 h* C7 m2 m5 }9 j6 C参加一些讨论是增加积分的最好办法。

ayeqiu

回复 tpwang 的帖子
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$ j. T/ n: ~0 k# Q原来是这样啊，谢谢你！