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Volume 25, Issue 3On the cover:
9 |, M Q, S# mEpidermal growth factor (EGF) induces fast and efficient mitotic progression, + @1 u. E. h. x5 I+ d
particularly in cancer cells, by accelerating centrosome separation. Thus, a " O; P* B: U) ^% B" X0 i1 ]. t' X
HeLa cell treated with EGF proceeds faster through mitosis (left path) than a
; } J1 r) T" U0 A; {* Bcell left untreated (right path), as visualized by confocal microscopy. 8 C' [1 R; \; o( a3 B% Z& E
H2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
2 c6 ?: a- Q, O6 eenvelope. For more information on the effect of EGF on centrosome separation and
+ S) i. ~+ l7 e. {' x/ \# Dmitotic progress, and on how this may relate to cancer therapeutic strategies,
( ^# p9 g+ C( W- d# |see Mardin et al., pp. 229–240.
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发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
