|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
) D3 B- t+ f5 h2 x: F3 T# d
 / K$ [0 V* o! @$ F( ]
Volume 25, Issue 3On the cover: . C& L( L3 k7 H) q G' v
Epidermal growth factor (EGF) induces fast and efficient mitotic progression, ) \3 G( B$ b4 U7 T1 }8 s
particularly in cancer cells, by accelerating centrosome separation. Thus, a - s# U1 G' m$ [4 \6 |" k8 Y' B
HeLa cell treated with EGF proceeds faster through mitosis (left path) than a . Q1 K. t9 C& C; X" d
cell left untreated (right path), as visualized by confocal microscopy.
: ]: x; [9 i0 e. g S$ WH2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
6 B6 ]6 I4 Z( |, T7 k8 Wenvelope. For more information on the effect of EGF on centrosome separation and ( E1 O5 J# w, c( a
mitotic progress, and on how this may relate to cancer therapeutic strategies, 9 d! g6 A0 J, C+ F g' e
see Mardin et al., pp. 229–240.8 L' q3 o9 E0 N6 F3 l
& k4 ^. @" `& X3 P' u
|
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
