|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
1 w. }4 v0 r* i; q
. l- O) @) w1 P1 Q& A, ^6 N$ eVolume 25, Issue 3On the cover: ; X7 }8 Y# O: w6 W- s( A/ B& D
Epidermal growth factor (EGF) induces fast and efficient mitotic progression, 1 z: `, x: C' t. R6 I3 P
particularly in cancer cells, by accelerating centrosome separation. Thus, a
5 H- X9 a. k( e' sHeLa cell treated with EGF proceeds faster through mitosis (left path) than a 9 a' a4 H2 |2 L4 P) j" ]
cell left untreated (right path), as visualized by confocal microscopy.
# t8 V* N( `, }% E8 E2 ?/ VH2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
# ^- k1 `: r. x& A1 Y% Genvelope. For more information on the effect of EGF on centrosome separation and
$ `8 X% W, K% L0 E) O) K0 I% e6 _mitotic progress, and on how this may relate to cancer therapeutic strategies,
. T5 N/ ~' N& r2 |2 v6 D/ osee Mardin et al., pp. 229–240.5 R7 ^; \% ^8 p
6 g/ q$ {" z8 b+ e) Z8 C2 Q |
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
