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4 [' n; a" r/ ~' I* lVolume 25, Issue 3On the cover:
8 z% x5 [& P s5 H9 j$ VEpidermal growth factor (EGF) induces fast and efficient mitotic progression,
; E- v+ {5 A" Eparticularly in cancer cells, by accelerating centrosome separation. Thus, a
$ y& y& f+ e- I6 \HeLa cell treated with EGF proceeds faster through mitosis (left path) than a
; q6 u) y! j8 Pcell left untreated (right path), as visualized by confocal microscopy. 2 D3 H9 s. s" j
H2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
/ K) w9 C! Z! l l8 X* F: V4 G* Cenvelope. For more information on the effect of EGF on centrosome separation and
# o9 N0 q7 m# Emitotic progress, and on how this may relate to cancer therapeutic strategies,
2 W5 s8 p! v4 V7 P& N8 Bsee Mardin et al., pp. 229–240.
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