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: F6 B- J: x9 U+ f+ i5 {
: j" P( b! s/ s2 G0 j$ d) ^% f3 {) AVolume 25, Issue 3On the cover:
- \2 V1 y) M7 KEpidermal growth factor (EGF) induces fast and efficient mitotic progression, Q% _% W X6 C+ p
particularly in cancer cells, by accelerating centrosome separation. Thus, a
3 L+ O Z& H4 R% h8 g& bHeLa cell treated with EGF proceeds faster through mitosis (left path) than a
7 m* u2 ~: D2 Qcell left untreated (right path), as visualized by confocal microscopy. & A3 j- N+ I8 A7 z5 b( {4 Q
H2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear / M- x) E- L/ |6 R6 f: s
envelope. For more information on the effect of EGF on centrosome separation and # Q8 F5 I& J- Y- y3 ?% l
mitotic progress, and on how this may relate to cancer therapeutic strategies, ) t/ I3 o1 k: g Z
see Mardin et al., pp. 229–240./ }% V- Z3 k" j- C. b+ c
4 G% t9 m, j' d1 F- ]
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发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
