|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
5 o/ Z0 z0 V' D$ z0 A1 n
W k+ a' D' }5 c1 OVolume 78, Issue 4On the cover: Neural networks control 8 w. k6 E4 n9 M. F$ s6 R+ g
intrinsic encoding of the circadian clock. Circadian pacemaking in the # }# u9 b$ Z |
suprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and ! V) p0 u) X# M" |/ K) U7 h5 n
intercellular properties, with the latter still poorly understood. In this issue $ _1 \; p3 c- w( y
of Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level % |0 E4 f/ k$ ~3 S/ y9 ]8 u9 z ], w
encoding of circadian time, showing that specific activation of Gq-Ca2+ axis in . s( z9 C5 a4 x; U7 E
restricted SCN neuronal subpopulations reprograms encoding of circadian time by + b/ u5 j6 K0 D* W- F- |' g
the entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic
$ U3 v$ S1 v4 u1 o2 mconnectivity. Concept by Marco Brancaccio; cover illustration by Joanna , D; X( |; R3 I5 u6 K
Westmoreland.
0 M+ Z4 t* L" P G5 r
+ `5 s" v/ {/ R5 k, e4 P. j5 q! x6 E |
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-23 23:46
