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9 c) p8 U7 `2 eVolume 78, Issue 4On the cover: Neural networks control % K* l1 K" m" A7 u
intrinsic encoding of the circadian clock. Circadian pacemaking in the + X' F( a9 c" g% U0 v' H
suprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and
5 N7 M v4 }1 ^+ @& Vintercellular properties, with the latter still poorly understood. In this issue 7 G, P2 o' K3 z3 P, F
of Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level
* X- A* \. R( D7 E( v3 U# X( lencoding of circadian time, showing that specific activation of Gq-Ca2+ axis in
( W( s: h0 S _5 b4 Arestricted SCN neuronal subpopulations reprograms encoding of circadian time by
( |9 [% _1 ~0 o1 s/ {the entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic 7 N g. R2 ]' g0 @: a
connectivity. Concept by Marco Brancaccio; cover illustration by Joanna ; O N! @, x0 l. Y, }. L
Westmoreland.; K0 n" g1 O5 ?/ K4 h2 Y; q4 t6 j
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