|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
4 Z6 v) p# {: i4 z8 F" e
0 M; t, [4 g$ |! @. H% oVolume 78, Issue 4On the cover: Neural networks control 4 s% C. r, q& A8 j m
intrinsic encoding of the circadian clock. Circadian pacemaking in the , R. ?& J! R9 p8 P4 Y* s$ x
suprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and
4 Y4 C& E" {# t- X9 ~8 m' M" wintercellular properties, with the latter still poorly understood. In this issue . J* b" s ]9 b+ j, v7 y3 l) ^6 W A
of Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level
" P1 e' O9 [6 N3 E! rencoding of circadian time, showing that specific activation of Gq-Ca2+ axis in n" Q) e( p- O
restricted SCN neuronal subpopulations reprograms encoding of circadian time by
c. P6 o1 i& q& s9 y' cthe entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic
: j# h/ a" W2 G% O; z1 iconnectivity. Concept by Marco Brancaccio; cover illustration by Joanna
5 ~5 } F! b" T, kWestmoreland.
/ [$ P8 u$ e( ~& s: \# \( e
" _8 f0 S0 O0 @$ a/ O; Y/ j8 C |
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-23 23:46
