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- 积分
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2013年12月5日 Cell0 h3 y4 y4 K# ~5 d6 M( G4 `9 e7 a
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5 December, 2013 Volume 155, Issue 6
) }: H4 c, n& OOn the cover: The nuclear pore complex
$ C; \! v+ P [0 ^3 u( d) U, B2 y; m(NPC) is a large multisubunit structure that regulates the exchange of 4 \& O F+ D+ i( y' C% f+ O3 A- h
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. , v: P0 S9 D+ a: z; z: M
(pp. 1233–1243) use an integrated approach to establish the blueprint for the
1 d. C- G! z( T: sstructure of the NPC scaffold in humans and explain how changes in the diameter
6 n. ?0 M& {6 ?- Z. b' z+ S8 rof this scaffold enable the transport of large cargoes. Cover artwork by Khanh 6 n* K4 @- L& f0 w
Huy Bui. Original photo by Alan Levine.
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