Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.
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2 |2 ?4 {! K- r, q0 V: {! R: ?The deepening of our understanding of normal biology has made
9 v3 x3 M  A% O- K2 n& uit clear that stem cells have a critical role not only in the generation of complex
! d: C1 F6 u  u* }. ~/ d) P( {% r3 Gmulticellular organisms, but also in the development of tumors. Recent& V3 z6 Y2 e: L, ?9 E6 w1 L
findings support the concept that cells with the properties of stem cells are integral2 z% R+ P6 }+ U3 O1 N$ e
to the development and perpetuation of several forms of human cancer.1-3 Eradication% O' z0 U3 V9 h( l# P# z- h
of the stem-cell compartment of a tumor also may be essential to achieve stable,0 |" A& D6 r5 M5 L' T% q6 J5 q
long-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of- x& I9 U$ h. I" U6 q, c" f
the properties of stem cells have made specific targeting and eradication of cancer$ O8 q: o2 K; |1 ?, C  r* K
stem cells a topic of considerable interest. In this article, we discuss the properties
8 R0 W2 S$ \6 x+ R- Sof cancer stem cells, outline initial therapeutic strategies against them, and present! F. ?! |1 [5 M4 M5 y3 ]
challenges for the future.4 v. w( P3 V! s" {! I$ Q% m! c+ a# x
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efool

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Fischer3

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ahmusht

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Chris

like it
- j/ o0 ?7 S$ ]3 bthanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good