|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
: J1 i, C; e2 R4 M" u3 |' A! P0 N
# H; \- h2 K" I9 xVolume 78, Issue 4On the cover: Neural networks control O1 F! w1 p. s9 }) k$ R8 a W
intrinsic encoding of the circadian clock. Circadian pacemaking in the / O# O$ }; k' z' x v2 `
suprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and 7 M1 @# K, ^0 Q3 z
intercellular properties, with the latter still poorly understood. In this issue
# |. y. h( [7 m- h6 K# Kof Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level . l& Y& p3 A3 F2 i% L8 P2 B
encoding of circadian time, showing that specific activation of Gq-Ca2+ axis in & [6 u8 l$ y. ^
restricted SCN neuronal subpopulations reprograms encoding of circadian time by 6 g( y1 T9 B6 o" W
the entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic 3 t9 g# l0 o# H0 D- T
connectivity. Concept by Marco Brancaccio; cover illustration by Joanna
) q1 V9 E! B) h! _. H% s9 AWestmoreland.
/ K8 _: j) Q& X0 d
. t( W% W* Q y- A8 N |
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-23 23:46
