[全文]丁盛Nat Methods新文章－－提高iPS诱导效率200倍

芷瞻

Nat Methods. 2009 Oct 18.【Epub ahead of print】* h# }: V0 B' Z4 R+ U: `

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A chemical platform for improved induction of human iPSCs.2 D/ B6 B( o4 V3 c+ O

% o5 O$ e  Z( ^3 R5 [* M4 ~Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S.
" k, I$ D/ F' y5 b# |Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA.7 [$ a. F+ a! r! k* |. J
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The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, nonviral methods for reprogramming human somatic cells.
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0 v  |( g  ^+ H3 v2 v) YPMID: 1983816, g. ]; A9 c  E* L% S
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jianlindunev

学习中，感谢

好玩301

怎么下载不了了？仍然感谢

sunyucheng

ddddddd

应菜

能下，谢谢

lorey

顶！好文章

dengyanfei

非常感谢

carolshf

非常感谢

风源

感谢

mmssyyee

请问你有没有这篇文章的methods呀？我在网上下载不了，有的话能不能给我一份啊，谢谢！！！