1998-nature-Dendritic cells and the control of immunity

andylee824

   B and T lymphocytes are the mediators of immunity, but their function is under the control of dendritic cells. Dendritic
: W+ o  f  h/ L1 u3 v: g* _cells in the periphery capture and process antigens, express lymphocyte co-stimulatory molecules, migrate to
. i0 K1 q: r* ^7 w6 [4 Ulymphoid organs and secrete cytokines to initiate immune responses. They not only activate lymphocytes, they also
. Y, K+ W! V) C6 Stolerize Tcells to antigens that are innate to the body (self-antigens), thereby minimizing autoimmune reactions. Once( \9 N5 B3 O  I- K
a neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell
+ T+ m" R- T/ O0 _; _. \# m3 Wbiological analysis. With knowledge comes the realization that these cells are a powerful tool for manipulating the
7 G% }" @. E1 x+ J% n! Gimmune system.

andylee824

自己顶一下！

andylee824

自己顶一下！