《细胞》[Cell]12年4月27日出版pdf全文

nero1981

5 f( Q& J7 \& a) w& PVolume 149, Issue 3
4 r) R0 A2 ^3 e3 S3 B4 C$ MOn the cover: The combined activity of neurons in the brain generates - m5 l" a2 ]) b  i& h" q# b
oscillatory rhythms, or “brain waves,” that can be detected by 5 n( w/ a9 Y' t. D5 F: g+ J
electroencephalographic recordings. Verret et al. (pp.708–721) found that these / q6 t8 Q3 E6 d: M& H: p3 L( ^2 }
brain waves, which are represented on the cover by an undulating pattern, are 9 `4 q. t0 x. N
altered in mouse model of Alzheimer's disease (AD), and the changes are linked
0 Z  l, N3 G- Y4 bto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring 0 d7 b; d, h5 Z; A
Nav1.1 levels specifically in inhibitory interneurons improves oscillatory 1 G) ~3 ^$ [" t6 H3 W3 M# |
rhythms and memory in AD mice, offering a new therapeutic approach for ! {6 p4 ~; [' j
potentially treating cognitive disorders. The image was created by Arantxa 1 V4 d5 F8 w' c2 b; @; \; d7 M( N
Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop 8 \' a  s( e6 `$ O% U9 }
(electronic recreation).( R! w, L7 G* _7 G1 Y
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menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

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不倒翁

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eley

ding~~~

cytobiology

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zorro

回复 cytobiology 的帖子- c/ r. k! _( e) A( b
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你的积分等要到50呢

markllq

谢谢% @# @, U' L& {* g: Z5 D: V

191225092

看一看，瞅一瞅。