[全文]丁盛Nat Methods新文章－－提高iPS诱导效率200倍

芷瞻

Nat Methods. 2009 Oct 18.【Epub ahead of print】; k/ b5 ~' g9 {7 I+ l6 o

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A chemical platform for improved induction of human iPSCs.3 }" Q* y0 }5 T
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Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S.& i$ Y7 _# {) M
Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA.( z4 h& R7 y0 U

( E+ v# z5 A, e$ _The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, nonviral methods for reprogramming human somatic cells.7 e/ u$ V2 _1 ~) N# E8 w
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PMID: 1983816% v# g; n; M+ h$ X' V/ F, v+ i8 t$ z
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jianlindunev

学习中，感谢

好玩301

怎么下载不了了？仍然感谢

sunyucheng

ddddddd

应菜

能下，谢谢

lorey

顶！好文章

dengyanfei

非常感谢

carolshf

非常感谢

风源

感谢

mmssyyee

请问你有没有这篇文章的methods呀？我在网上下载不了，有的话能不能给我一份啊，谢谢！！！