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发表于 2019-1-8 21:46 |只看该作者 |倒序浏览 |打印
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"genetic mutation" should be exactly as "gene self-editing"2 ^7 b: C8 D) k) C" z+ U" G+ X+ s
2017-12-1 13:17
$ m5 F7 I- f0 u. f5 tBioreactor in vivo would be the terminator of illness.- _% u' S( C- A" j
2017-11-20 23:09" L1 F* m  o4 Z% v7 g
renew tech:剔除衰老(病变)细胞占位可以恢复青春。3 ^$ O8 e( L7 O, E0 J
2017-10-23 12:50- s5 A% I, b6 Q  A; y. P
魔不疯,鬼不魅; 道非盗,仙非妖;神无形,兽无极。
4 _* N% @2 Q# u2017-9-30 10:58* k7 E6 x( |: V0 X0 ^
Life 3.0——from decoding and coding to reading and writing
* `* C5 {2 b) C* c7 o4 N8 y/ r2017-9-21 22:32) a2 y( \9 o. P/ \
理论创新:亮明立场——先颠覆,再完善1 g  o" M: U2 A- s2 s9 X
2017-2-7 00:07
, Z0 m5 I6 E! }$ q1 V干细胞第二定律:与细胞外基质共同构成多潜能;" u. M% r( u! G/ t, W/ u1 |6 F: e
2017-1-3 11:14, [, L1 j$ T+ {+ m( b/ ?( }1 q
干细胞第一定律:全生命周期保持增殖分化能力;- z! h4 L$ j0 r( w
2017-1-3 11:13
& T/ w2 E  j& F/ [3 O' LNgAgo——Never give A guideline operated!
% ~' {% S9 K' D6 \6 Q* X2016-12-1 10:09
9 x- t; P/ e" z; f/ @表观遗传—— 一切皆可改变  一切皆有可能
1 a9 L# F5 r0 [2016-8-17 23:37
0 ]8 z0 E) {7 K! j, G子曰:吸血鬼疗法——养儿防病 养孙防老  _/ w& R7 \* S% `0 A; W0 v4 j
2016-5-23 12:05
3 ?' \. S+ E2 gNgAgo——Debug tool kit for mammal cells
. y2 N- E. c" f1 \2 T: e2 e" d2016-5-9 13:09( Q! E, [$ n$ ^; m& e7 D6 [
公理之外 皆需证明; 科学命题 皆可证伪。
4 a" f7 S' [0 E( L  {: ?2016-1-2 00:20
7 A" D, n0 P+ R* y( A低氧——破坏线粒体功能、诱发炎症、导致基因突变
# E5 ~- P" S9 e; `$ ~; F2015-12-16 20:193 A' M8 [3 g) ]" R' v9 M0 u
癌症——炎症部位组织再生过程中细胞去分化失控形成的幼稚化新生物。
, p/ o( X: M/ b7 `  {hcoohboy: 一个有趣的假设~但是没有炎症就一定没有癌症吗? (12-18 16:16)
- s5 f  O6 i& gsunsong7: 炎症与癌症同在,Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation[J]. cell, 2011, 144(5): 646-674. (12-19 19:45)' d( g. l4 ?* s% D  W, h
hcoohboy: 3ks~ (12-24 16:45)
2 A$ \+ o- N4 u3 @, a0 n; V& F2015-11-18 15:54- \' F! K2 k4 ^( V
抽象世界与客观世界的真理判别标准是不同的: 在虚拟数学世界里,逻辑是一切命题的唯一审判标准; 在客观物质世界里,证伪是一切定律的最终审判依据。
7 w4 c/ [. J" h& b- |2 `* L2015-5-20 14:13+ x/ {% `* }* \6 _; {& R
传统生物学将死:进化论=自然神论   基因轮=宿命论   细胞论=活力论翻版。    现代生物学曙光乍现:系统生物学=数学 结构生物学=物理学 合成生物学=工程学7 M% Z% X& w& ^2 |
helong: 系统生物学是把细胞、基因、进化、物理学、信息学(数学)、工程学等都打包起来的所谓新学科,目前只做到了简单组合,还没有达到系统集成阶段。合成学更多偏向于化学。 (4-21 19:28)& p+ o# o% Z% G9 ?  I  V% U& J4 O
sunsong7: 方向对头,努力总会有结果的 (4-21 20:05)
7 j* N" a8 D, E7 l  {2015-4-21 16:46( U3 ]; t) O' \
search and research is just disassembling the creature.$ Q: ]6 g8 Q" w8 H
2015-4-7 17:01/ \3 z; q! r# A% N4 V$ P
selection is  the act of intelligence
" T3 A9 \2 F. X# |& |, R5 {2015-4-7 13:49
: c' l7 Z. Z6 P% f+ X2 Z; [Genome fusion create neoplasm4 d! H& v$ O# |$ ~+ Z  D
2015-1-20 13:10
) U9 @1 a/ }$ c2 S0 V; ?6 VSTAP——Stupid Trick  Against Professional - r3 s" i3 f3 Q. U" B8 \
2015-1-1 19:29
  q3 b$ W1 Z! G  d9 S( ], ~8 h4 Cinformation=structure=negentropy' ~9 d; Y. b8 f' i. q; K
2014-7-22 17:36
" [6 K/ ]! X, f1 LNatural mutation does not result in new functional genes 
0 I0 s4 o* Q2 Y2014-7-3 14:060 ]3 a" ]$ U" c/ l: L
life is wisdom creation instead of natural evolution
4 w3 B( N$ I4 K* \3 E2014-3-27 09:33
5 d& X2 y1 k" ilet us explore the source code of life !& P# R0 E' [  H$ `& o  F# m
2014-3-11 13:118 a  Q5 k" M# |0 V) e) @' E' P& U
bio-manufacturing——processing,machining,casting,printing,3D prototyping,duplicating,cloning,life replicating.) {7 g! w* E8 ^' Q9 l& [
2013-10-7 23:06" Y( [# ?% T* Y1 J
induced abortion would give the key for curing cancer 
, |! @5 v( i, r% P0 |2013-10-2 23:33
) K4 U8 o+ a8 M$ Q+ J2 x) j3 D) _& S“key breakthrough” in molecular biology are entertainments7 v* [4 i3 V; e" A% X' }! b
2013-6-16 11:50+ D' n. B8 x! G  _" x5 d$ z3 H' _
Rules Of Living:trial-and-error exploring,survival takes the legitimacy
; q3 U  W8 m. i+ ~8 S1 Y) O; w2013-6-16 11:27
$ w  s; J- {$ J+ V& s0 R1 wLife is a set of debuging programs
8 B* m9 ~; [# p7 s2013-6-15 18:40
( e, A; x: c- }8 x& w8 d* X2 }current biology is closed,destined and agnostic,it is  the only contribution is to kill cells5 o' r# |# E( K7 t; x' W2 j
2013-5-2 08:54
1 C, p% Q. z. Z. pinformation,energy and construction are the new base stone of biology,instead of evolution,gene and  cell  tales
4 C2 N% X& |0 O) d' v2 D, J2013-5-2 00:512 X, u9 N4 O/ u4 u0 H
virus is the messager of  the universal life network5 r. ~1 n. ]  p
2013-4-18 14:33) N7 f2 l% I! ~, x! O
Genetic information doesn't improve cancer risk prediction
3 I6 Y4 W$ k3 y8 g; `  G2013-4-1 09:20
- h. q. }9 j# _" G2 |$ L8 x# FThere is no early diagnosis of cancer,but early prevention of it: \9 [- N9 U! O* @" p
2013-3-27 09:17
( O; X, H: v9 J0 W9 v" hhypoxia maintains stemness or carcinogenicity
6 R  t4 r2 J& e# P! k7 U2013-1-2 05:21
$ v% D! V! d: ^, g/ m5 R% m$ |cancer is the living fossil records on origin and evolution of human being
5 a: B0 v8 H# y8 o7 \, x5 n9 c2012-12-9 23:31
. e; I, d& a+ H9 b# h$ uinformation island results cancer
& ~6 D  w4 m! F7 r3 r" Z2012-12-9 05:23
% p$ D  u3 A4 f  C0 f: [" U) B; ?life is digital game
' S' R- R3 h6 N7 @2012-11-10 00:177 i* E. d) d  j
cancer ——severe abstinence reaction of cells to niche addiction1 |+ f7 y1 |+ V4 l5 }! s
2012-9-28 12:11
" X/ A5 o! {( p! H未来生物学终将回归物理(熵)及数学(分形)的美感
. i, ?3 i0 H* J; O' h! E4 u7 ~biomater: 熵理论适用于任务物质。。。。也适合于生命 (9-26 09:28)
* e& I) Q& x+ y2012-9-25 21:22( J: g: `( a* F  h! E/ {, {
membrane holds the key to life* K' R: u! b3 _$ d6 o& g6 y
2012-8-19 20:24: q0 L4 g' ~! ^9 _
Cancer is the default state of cells8 }- k/ p$ v( ?7 [, D2 e0 c' w
2012-6-26 22:17( S# R% u3 j' W1 f" r4 k* [$ ^
mainstream cancer theories could be overthrown!
, F- K9 G3 I3 E. M% D. S2012-6-25 15:43
1 W5 g! [5 C% O9 J0 Q7 U3 Ucarcinogenesis has nothing to do with the gene mutations but is  the result of niche reprogramming...
1 y) [# T5 ~, D; t; G  C7 A2012-6-7 09:36! P! l- N8 `. \
every living organism connected with the water, one cell one world
0 q7 D3 r2 r! X) j" D: h2012-4-19 22:06+ U8 V* E! P1 [( p$ q. N4 d
chemical structure of cancer cell determines it's biological function...3 g& n& \) @% p1 u9 r! x
2012-4-7 17:56
8 s) B! s# ~/ }Mann tracht und Gott lacht
2 o2 N5 ]6 }2 K* d# _) i2012-3-24 21:345 f5 k, B* a. D/ ^* R
Darwinism or genetic determinism is a fairy tale!/ o) E! H$ u& W0 K2 P. r  l( w# i
2012-3-13 15:18
, n, B- ]% @3 T5 aniche isolation is essential for cancer speciation
7 C7 t  \* x: n2012-3-12 12:07
& ^; C& g. R  e: I8 v2 ]Hybridization Creates New Species,Mutation results species extinction
0 ?: t+ k# ^! P6 c& X2012-3-11 18:21
  x: j6 w% C) C# E. F; TROCK may join the niche reprogramming...
6 [0 l$ l6 x1 c1 D2 I0 G. @yuhaoze: 这是篇文献吗? (3-9 10:41)
( f; c+ c, q7 Y7 asunsong7: http://www.stemcell8.cn/home-space-uid-6268-do-blog-id-1211.html 突破:病人体细胞及肿瘤细胞长期体外培养(附原文) http://www.stemcell8.cn/thread-51419-1-1.html (3-9 10:46)+ I2 ~/ N. I, [9 s  ]
yuhaoze: 啊, 我看过这篇,还顶了呢,谢谢哈 (3-9 14:37)
8 ]7 c9 ^$ J. ~  R( P7 g" q$ n  e4 ]2012-1-19 10:52) B4 @9 e! x& M/ f# ^8 v
oncogenes are pseudoscience: D" M; e: n+ T$ X
2011-12-29 13:55
1 L' A' @5 M2 a' K' e# _" ~gene mutation leads to variation or extinction, not new species2 _" C9 h9 e- E( N. Q
2011-12-29 13:28
) O/ z& B; K3 @. @  K; l$ J  foncogenesis is non-Darwinian event" P2 [7 ^) d+ L
2011-12-28 22:56; l4 ]6 a0 w8 V5 C! y
disorganization activate neurogenesis activate oncogenesis   
% K' j. u# }. k" `  h/ y8 T2011-12-22 23:38
1 j) ]5 A3 B7 x3 O& b5 F1 B2 DMSC is cell feeder,tissue scaffold,immune firewall and biological glue
5 c7 U0 i5 m8 ], N2011-12-19 19:46: w; q- t- n! |
cancer is Noah's Ark(species carrier and life explorer)
# \) ?" m& M# k8 j2011-12-10 09:46
) X; m: f) V; j1 B* k. f- n, Fcell fusion create new species, gene mutation induce variation
+ k% ]! w1 `; o4 E+ l7 r9 o2011-12-10 09:367 g! J- `5 z2 g1 O' B
GVT will be cancer terminator, Cytokine storm will be cancer preventor% }3 f9 y+ O" U( V# l+ k+ [
2011-12-8 12:56- R, [- T; R! z1 Y
cell fusion results regeneration,reprogramming,neogenesis,atavism; cell division results differentiation,apoptosis,senescense,development;
0 t/ O$ f! l3 z1 Z- l3 P2011-11-27 14:54
9 Z$ `9 i7 m+ z; ~2 _' ^* }# |Cancer is between protozoa and mesozoa, not metazoa...
( R. M+ H, n7 _  A( E( O& P2 U2011-11-27 00:25
9 i* S/ s6 U% S$ F/ W1 @6 w7 F+ C; D$ dcancer is neurological disease! haha,I got it!
1 k; L! K, l. F7 n! w. d% W2011-11-22 22:06
" G, B: X; p) _# X( g6 y5 Wyou are cancer,fetus is tumor. 佛曰:汝既是癌 癌胚如来
: `  m/ n, ~+ w  p! D- v9 }2011-11-12 11:27
+ b  I8 R& h0 N3 Bcancer is the ecological invasion of hacker...
9 L7 q8 k  N" t% i. B2011-10-5 10:317 [3 f5 V& g, G. t6 j7 E& ?  g
microRNA is  negentropy?
8 g# }7 q1 k' N) e2 R( C* A5 T& O2011-9-24 00:485 A( r9 u  f, x+ I' f# h8 g6 I
cancer is the social problem2 [* n9 Q; A( R
2011-9-9 23:33
4 u; B# q, r) K; q! ^0 ^% jScience is the games of nobleman or madman
0 O; k1 d4 n' W; f2011-9-2 15:03. k2 q: l9 q8 Q
cancer resulted from disturbance of biological liquid crystalline state of ECM
& i6 E5 R  E# r  ]3 J2011-9-1 20:13- I6 w9 E$ U5 M5 D0 k' E
niche n-dimensions——space, time, momentum and entropy; energy, material and information flows; physical, chemical and biological factors;topological, thermal, and fractal influences...5 W/ O# ^  f9 a9 \5 a
2011-8-13 00:37  c6 A3 z' n) E! z
Second recession is coming?4 m' r: X9 L6 F( Q+ y+ a
2011-8-9 23:58
. v0 ~+ T* M2 M% a% icancer may be from sexual reproduction of somatic cells.
7 ]0 x9 L% t# A! M0 J+ A2011-8-7 00:16* r1 O7 T  G; z
who determine gene? genetic determinism is fatalism!
2 k9 P! g2 T- i* O( z2011-7-30 11:268 I) @0 o: b8 j
niche reprogrammabllity is the key of solving cancer problems...
3 P$ f' b) y3 w- qsongtianlong: i can't agree more!!!O(∩_∩)O~ (8-14 20:42)2 }" y! \* W4 p+ }+ n
sunsong7: hehe. thanks for interested in this topic, welcome future discussing (8-14 20:54)* I" V2 _9 h5 g" Q% [
2011-7-24 01:248 W+ ~: d2 p0 a9 t/ ?
cancer results from acquired genetics alterations.2 y- v) S3 n7 m7 z0 _. j' M# o
2011-7-20 21:37
% I9 W* s$ L' |# m4 F. sCSCs are the low differentiated cancer cells in G0
2 F% _5 N7 {8 R$ I+ X2011-6-29 16:30
& D6 B1 d" q: B1 h8 w% i- b9 QiPS future——in vivo direct reprogramming ..." u+ j0 v" O/ V' h
2011-5-31 15:20
2 `. |/ Y' ]" rniche reprogramming——cell fate will be manipulated by cytoplasm - microenvironment interaction http://www.stemcell8.cn/thread-40755-1-1.html8 L+ z' F; E" s0 k2 F7 r, F2 d* f
2011-5-31 01:28/ ^4 c: s! t% c) a$ W0 e
all the somatic cells of Mammals are totipotent !
: p4 }4 d2 Y- P. A# Z% W2011-5-22 22:22
# y$ b3 G8 o: g' l+ B7 y- N+ C, ImiRNA——The manipulator of  cell fate!
2 z! H/ @! ?; b2011-5-20 20:21
% v" c( b8 K4 w) f4 w, }2 z" q8 T, R《Cell Stem Cell》means “cell is stem cell”   活细胞就是干细胞?5 N* j* |4 T6 N9 C7 y# s
2011-5-17 12:38
  R+ \* y2 E# i6 }5 J% V8 w4 Ycancer —— good nuclear in bad cytoplasm!RNAs are cytoplasmic determinants determine  cytoplasm determine cell fate! division is differentiation is cancerous is life !
# l) L% l1 E* G/ d- r2 p$ i2011-5-11 12:31
6 q4 |, _& N$ ^0 h' Icancer results from cell dedifferentiation...
. W5 o& r- }" J0 F" G2011-4-28 18:07
! i" j0 j2 L+ idifferentiation——asymmetric cell division !
5 r* c; @3 X0 x: ?2011-4-28 18:04
+ L) y7 g  a# ^/ q- S0 m) Ccancer origins from the regenerative cells!$ p, O6 ]+ y$ k& y% z
2011-4-28 17:52% x& p  Q# n. R
Proliferation is differentiation potentiality!
' |9 P& M" }, u4 o0 I6 l. I# N( q2011-4-28 17:49& _3 _# I- k" c6 e$ A3 D( Q  S: z$ W
iPS——the key of Pandora box!5 F0 m+ K) C3 S1 |0 f; ?
2011-4-27 22:36
& \8 b2 g2 p0 H2 \: Q" t" \Aristotle— "The whole is greater than the sum of its parts.") L9 n0 x1 ?- b( B3 H1 n& T
2011-4-27 00:20. t) s# {) h; t: p( y4 O6 s: V
cancer——atavistic cells9 b2 `6 v( }- i6 I
2011-4-20 00:20
  |1 w& C2 v) wcancer——cellular atavism!* w2 j' E& m5 a
2011-4-20 00:18
0 J9 z9 h3 ~2 ?0 _cancer——evolutionary ancestors of mammals.
# k" S4 f& N, k- `2011-4-20 00:09
! ^! J) E: b$ @1 n- E0 e肿瘤是细胞自组织缺陷的产物 , x* E2 J( M- R) f( f
2011-4-17 01:41% o; O7 P: h8 s8 a' h! Q
cancer——Metazoa 1.0
1 G; M) H" [) O( Z; A2011-4-17 01:00/ u6 `, s+ |# V9 X' Z$ c, l
US——the Axis of Evil!8 ~! ^. d% [4 \! p* O- \
2011-4-4 01:19
* ~& K; s& I2 B$ [4 v美国是世界的邪恶轴心!: F2 h8 `  K$ Q
sunsong7: 沁园春.血               ---作者:萨达姆   日 本 风 光, 千 里 地 震, 万 里 海 啸。 望 仙 台 内 外, 废 墟 莽 莽; 东 京 上 下, 顿 时 逃 逃。 核 站 爆 炸, 世 界 惊 涛, 地 震 海 啸 试 比 高 ... (3-22 21:25)! H# E8 s% X. _) _; K* U7 g2 I
2011-3-22 19:06
6 u8 w& @3 e) l+ \teratoma is derived from endogenous iPS!( D+ w; q1 v& A* J! w
2011-3-15 21:440 `% d" Y8 P) G8 a6 l
ips is a luxury gambol on  ! C  W3 L( u; S9 g
2011-3-3 14:50
. f  U3 A7 y6 }2 bcancer is intermediate of species evolution
' A1 }) v' p( _8 }/ d2 K( O2011-2-12 12:29
; f; r3 N, b2 y. k3 kstem cell now is on the eve of coming medical revolution- }: j9 s/ d, q" q' x
2011-2-12 11:20
2 J& O' b& ~1 l( _  E# t/ ~Inflamation is the reprogramming process of somatic cell in vivo!
7 E# g& M: z3 |" U+ J5 o2011-1-31 14:49
( U4 L0 c/ r' R( ]so-called medicine is niche regulator!5 A6 H" ?( O- \
2011-1-23 21:45+ A) n& f/ U  u
endogenous iPS is the cancer initiating cell!
) b9 H; r7 \3 d8 l/ P4 I2011-1-17 16:47" @" H$ Y6 J2 I- K( M, _. Y
cancer is unicellular organisms!7 @: F: F3 n/ c: }2 b
2011-1-9 22:04
4 ?* n4 R+ [( U9 }Pandorabox Has Been Opened  c3 `, f& B# Z1 a* f
2011-1-7 23:24" d' [% Y8 Y/ u) y( d0 H
iPS is the Emperor's New Suit ! . a7 k. [. @" `! @
2011-1-5 23:50  D/ z& X5 `3 c& C1 m  r; ^
cell-free is the final solution of stem cell therapy
( @8 i0 e7 I5 b( b% ~2011-1-5 21:46
. ~) X: V7 ]* |0 d' Xniche is telling the story of stem cell...
6 h3 j: [0 _  _( L2010-12-29 17:32
9 o/ n3 S2 e  z% ^' X9 Jcancer results from reprogramming of somatic cells- Y# y% X1 J2 X$ w* {( B
2010-12-25 18:56; m' ^, N  B9 @9 G3 D9 h
cancer——good cells in bad niche!6 L' [5 D! k" _1 Q# Q4 @9 E& C
2010-12-25 16:025 V3 w7 k* x5 b' J- ]8 Z
cancer无罪——制造产生罪犯的土壤才是真正的犯罪!
/ ~% {: O$ Y8 ederon: 灰常同意,有相关文献么? (12-19 09:41)
: p' Z9 r" t) d! k/ s  ]# |% fsunsong7: 呵呵,请来参加讨论——癌细胞的发生可能是一种“返祖”现象? http://www.stemcell8.cn/thread-32073-1-1.html (12-19 11:33)
9 y/ B+ l: Z  Q! osunsong7: 问题讨论 http://www.stemcell8.cn/forum-re ... 709-pid-246202.html (12-19 13:29)
! U3 o6 q8 Y* ]* v8 ?" s7 _2010-12-18 15:542 f% O; _+ j+ M( j- v
子曰:上善若水 大成若缺——干细胞治疗的终极解决方案将是不移植外源干细胞!, d0 h& ~: h/ @& n. m
2010-12-15 15:07
0 ?; H* i0 T9 Z: q3 L老狼的记忆——大洪水- Q6 x7 P' _4 Z: O3 J
2010-12-13 23:257 H3 D2 }! L1 V& b1 r& R, F
can cancer randomly differentiate into norml cell in vivo  & M6 u# ]2 H$ d# K
2010-12-13 22:339 y  p1 H+ K9 |6 x" p
omnis cellula e cellula
; E  u) _  w7 \. o1 f  R2010-12-12 09:28
3 s# V( Y3 e8 p2 X( \6 ZStem Cell ——The Origin of Disease1 l2 k8 T) t4 |
2010-12-12 09:27# h0 r7 `$ P" a+ K1 [

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发表于 2019-1-9 16:31 |只看该作者
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